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          CA VIII rabbit pAb
          • CA VIII rabbit pAb
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          更新時間:2024-08-27 21:00:08

          瀏覽次數(shù):24

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          SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300
          • Source

            Rabbit

          • Applications

            IHC,ELISA

          • Reactivity

            Human,Mouse,Rat

          • Dilution

            IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

          • Storage

            -20°C/1 year

          • Specificity

            CA VIII Polyclonal Antibody detects endogenous levels of CA VIII protein.

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            Synthesized peptide derived from the Internal region of human CA VIII.

          • Uniprot No

            P35219

          • Alternative names

            CA8; CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII

          • Form

            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            carbonic anhydrase 8(CA8) Homo sapiens The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid

          • Other

            CA8, Carbonic anhydrase-related protein

          • Mol.Wt (Da)

            32973

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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