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          CAD (phospho Thr456) rabbit pAb
          • CAD (phospho Thr456) rabbit pAb
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          更新時(shí)間:2024-08-27 21:00:08

          瀏覽次數(shù):9

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          SourceRabbitApplicationsIHC,ELISAReactivityHuman,MouseDilutionIHC:1:100-1:300
          • Source

            Rabbit

          • Applications

            IHC,ELISA

          • Reactivity

            Human,Mouse

          • Dilution

            IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

          • Storage

            -20°C/1 year

          • Specificity

            Phospho-CAD (T456) Polyclonal Antibody detects endogenous levels of CAD protein only when phosphorylated at T456.

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471

          • Uniprot No

            P27708

          • Alternative names

            CAD; CAD protein

          • Form

            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase(CAD) Homo sapiens The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

          • Other

            CAD, CAD protein

          • Mol.Wt (Da)

            242984

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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