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          Amyloid-β rabbit pAb2
          • Amyloid-β rabbit pAb2
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          更新時間:2024-08-27 21:00:08

          瀏覽次數(shù):17

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          SourceRabbitApplicationsIF
          • Source

            Rabbit

          • Applications

            IF,WB,IHC,ELISA

          • Reactivity

            Human,Mouse,Rat

          • Dilution

            IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

          • Storage

            -20°C/1 year

          • Specificity

            Amyloid-β Polyclonal Antibody detects endogenous levels of Amyloid-β

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            Synthesized peptide derived from Amyloid-β at AA range: 221-270

          • Uniprot No

            P05067

          • Alternative names

            amyloid beta (A4) precursor protein

          • Form

            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            amyloid beta precursor protein(APP) Homo sapiens This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014],

          • Other

            APP A4 AD1, Amyloid-β

          • Mol.Wt (Da)

            86943

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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