A94683 Beckman貝克曼 CD8-APC-A750 CD8檢測試劑
- 公司名稱 江蘇省科學器材有限公司
- 品牌 貝克曼庫爾特/Beckman
- 型號 A94683
- 產(chǎn)地
- 廠商性質(zhì) 代理商
- 更新時間 2024/12/20 10:43:08
- 訪問次數(shù) 18
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Beckman貝克曼 CD8-APC-A750 CD8檢測試劑A94683
The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8α is required for surface expression of CD8β. The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain (α3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8α homodimer is expressed by NK cells and γ/δ+ T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Beckman貝克曼 CD8-APC-A750 CD8檢測試劑A94683
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