黄色视频不卡_午夜福利免费观看在线_亚洲国产精品999在线_欧美绝顶高潮抽搐喷水_久久精品成人免费网站_晚上一个人看的免费电影_国产又色又爽无遮挡免费看_成人国产av品久久久

    1. <dd id="lgp98"></dd>
      • <dd id="lgp98"></dd>
        1. 產(chǎn)品展廳收藏該商鋪

          您好 登錄 注冊

          當(dāng)前位置:
          美國布魯克海文儀器公司>技術(shù)文章>測量應(yīng)用案例-40-90Plus

          技術(shù)文章

          測量應(yīng)用案例-40-90Plus

          閱讀:259          發(fā)布時間:2015-6-8
          文獻(xiàn)名: Thermal properties and physicochemical behavior in aqueous solution of pyrene-labeled poly(ethylene glycol)-polylactide conjugate
           
          作者: Wei-Lin Chen,1,2 Yun-Fen Peng,1,3 Sheng-Kuo Chiang,1 and Ming-Hsi Huang1,2,3
          1National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan
          2Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan
          3PhD Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan
           
          摘要:A fluorescence-labeled bioresorbable polymer was prepared by a coupling reaction of poly(ethylene glycol)-polylactide (PEG-PLA) with carboxyl pyrene, using N,N’-diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole (DIC/HOAt) as a coupling agent and 4-dimethylaminopyridine (DMAP) as a catalyst. The obtained copolymer, termed PEG-PLA-pyrene, was characterized using various analytical techniques, such as gel permeation chromatography (GPC), matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), proton nuclear magnetic resonance (1H-NMR), infrared spectroscopy (IR), differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA), to identify the molecular structure and to monitor the thermal property changes before and after the reaction. The presence of a pyrene moiety at the end of polylactide (PLA) did not alter the crystallization ability of the poly(ethylene glycol) (PEG) blocks, indicating that the conjugate preserved the inherent thermal properties of PEG-PLA. However, the presence of PEG-PLA blocks strongly reduced the melting of pyrene, indicating that the thermal characteristics were sensitive to PEG-PLA incorporation. Regarding the physicochemical behavior in aqueous solution, a higher concentration of PEG-PLA-pyrene resulted in a higher ultraviolet-visible (UV-vis) absorbance and fluorescence emission intensity. This is of great interest for the use of this conjugate as a fluorescence probe to study the in vivo distribution as well as the internalization and intracellular localization of polymeric micelles.
           
          關(guān)鍵詞:bioresorbable polymer, fluorescence probe, pyrene, polymeric micelles, poly (ethylene glycol)-polylactide, PEG-PLA
           

          收藏該商鋪

          登錄 后再收藏

          提示

          您的留言已提交成功!我們將在第一時間回復(fù)您~

          對比框

          產(chǎn)品對比 產(chǎn)品對比 聯(lián)系電話 二維碼 意見反饋 在線交流

          掃一掃訪問手機(jī)商鋪
          010-62081908
          在線留言
          汉阴县| 南江县| 安福县| 于田县| 乌拉特前旗| 东光县| 乐平市| 丰镇市| 象州县| 木里| 潮安县| 白山市| 柳林县| 行唐县| 南陵县| 兴山县| 珲春市| 西贡区| 琼结县| 汝州市| 靖宇县| 上虞市| 云林县| 襄汾县| 于都县| 丹东市| 福州市| 安远县| 汾阳市| 嵊州市| 平阴县| 遂宁市| 友谊县| 汶川县| 连南| 拜泉县| 新巴尔虎右旗| 隆化县| 大洼县| 郯城县| 正阳县|