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        1. BPS Bioscience Inc.
          中級會員 | 第2年

          當(dāng)前位置:> 供求商機(jī)> Spike Trimer (S1+S2) (B.1.351, Beta Variant, Δ242-244) (SARS-CoV-2) Recombinant

          Spike Trimer (S1+S2) (B.1.351, Beta Variant, Δ242-244) (SARS-CoV-2) Recombinant
          • Spike Trimer (S1+S2) (B.1.351, Beta Variant, Δ242-244) (SARS-CoV-2) Recombinant
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          更新時(shí)間:2024-12-02 21:00:07

          瀏覽次數(shù):26

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          ●Purchase●DescriptionRecombinantSARS-CoV-2Spikeproteininitshomotrimericform,containingS1+S2subunitsandencompassingaminoacids16-1213
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          Description

          Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein corresponds to SARS-CoV-2 Variant B.1.351, also known as variant Beta originally discovered in South Africa, and contains the nine known mutations listed below, in addition to deletion 242-244*. The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.

          *Deletion 242-244 is known as 241-243 in some databases and on the CDC website. This is the same deletion. As stated by Tegally et al., Nature 2021: "We also observe a deletion of three amino acids at positions 242 to 244, which was seen in samples extracted and generated in different laboratories across the NGS-SA. This region is difficult to align; the deletion could potentially also be located at positions 241 to 243, but the resulting sequence would be exactly the same. "

          This product has been cited 3 times.

          Synonyms
          20H/501Y.V2, sars cov 2 Spike Trimer, South African Variant

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