目錄:MedChemExpress LLC>>信號(hào)通路>> WEHI-539 hydrochloride | MedChemExpress
| 參考價(jià) | ￥ 2456 |
| 參考價(jià) | ￥ 2456 |
更新時(shí)間：2023-09-28 14:50:36瀏覽次數(shù)：108評(píng)價(jià)
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| CAS | 2070018-33-4 | 純度 | 98.31% |
|---|---|---|---|
| 分子量 | 620.18 | 分子式 | C??H??ClN?O?S? |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號(hào) | HY-15607A | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)。
CAS No. : 2070018-33-4
MCE 國際站：WEHI-539 hydrochloride
產(chǎn)品活性：WEHI-539 hydrochloride 是一種選擇性的 Bcl-XL 抑制劑，IC50 為 1.1 nM。
研究領(lǐng)域：Apoptosis
作用靶點(diǎn)：Bcl-2 Family
In Vitro: WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells.
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