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Vafidemstat

CAS No. : 1357362-02-7

產(chǎn)品活性：Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.

研究領(lǐng)域：Epigenetics  |  Neuronal Signaling

作用靶點(diǎn)：Histone Demethylase  |  Monoamine Oxidase

In Vitro: Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease.

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