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Octenidine dihydrochloride

CAS No. : 70775-75-6

產(chǎn)品活性：Octenidine dihydrochloride is an effective antiseptic compound for skin mucous membranes and wounds.

研究領域：Anti-infection

作用靶點：Bacterial

In Vitro: Octenidine concentrations of less than1.5 μM (0.94 μg/mL) causes a greater than 99% reduction of tested microbial population within 15 min. Staphylococcus epidermidis is the most susceptible of the test organisms, and E. coli and C. albicans are the least susceptible.

In Vivo: The antimicrobial activity of octenidine hydrochloride (OCT) is maintained when applied to the skin of the hands and feet of cynomolgus monkeys. Aqueous octenidine, at a concentration of 0.2 to 1.6% reduces resident microflora populations from 90 to 99.98%. A significant reduction in plaque score is observed on the buccal tooth surfaces after daily topical application of 1% solutions of octenidine and chlorhexidine for 7 d; octenidine is more effective than chlorhexidine.

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