目錄:MedChemExpress LLC>>生化試劑>> Emicizumab | MCE
CAS | 1610943-06-0 | 供貨周期 | 現(xiàn)貨 |
---|---|---|---|
貨號 | HY-P9940 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 1610943-06-0
產(chǎn)品活性:Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research.
研究領(lǐng)域:Others
作用靶點:Others
In Vivo: Emicizumab (1.5-10 mg/kg, IV, 24 hours before tail-clip bleeding) partially corrects blood loss in a hemophilia A bleeding model, with an FVIII equivalence of 9 U/dL.
Emicizumab (3 mg/kg, IV) provides additive hemostatic activity when given in combination with low-dose FVIII (10 U/dL).
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