目錄:MedChemExpress LLC>>生化試劑>> Pepinemab | MCE
CAS | 2097151-87-4 | 供貨周期 | 現(xiàn)貨 |
---|---|---|---|
規(guī)格 | 5 mg | 貨號 | HY-P99407 |
應用領域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 2097151-87-4
產(chǎn)品活性:Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
研究領域:Others
作用靶點:Others
In Vitro: Pepinemab(VX 15/2503) (48 h) significantly inhibits the expression of glucose transporter protein (GLUT-1) and monocarboxylate transporter protein (MCT) 4 in primary human astrocytes CC-2565 and suppresses SEMA4D-induced reduction in glucose uptake by astrocytes.
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