目錄:MedChemExpress LLC>>生化試劑>> ATP | MCE
CAS | 56-65-5 | 純度 | 99.62% |
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分子量 | 507.18 | 分子式 | C??H??N?O??P? |
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 500 mg |
貨號 | HY-B2176 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 56-65-5
產(chǎn)品活性:ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
研究領(lǐng)域:Metabolic Enzyme/Protease
作用靶點:Endogenous Metabolite
結(jié)構(gòu)分類:生物堿 | 其他類生物堿 | 結(jié)構(gòu)分類
來源:植物 | 其他科
In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP promotes neutrophil chemotaxis in vitro.
In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.
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