英文名稱(chēng):Propargyl-PEG6-acid
Propargyl-PEG6-COOH
Propargyl-PEG6-CH2CO2H
4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
中文名稱(chēng):丙炔基-六聚乙二醇-羧酸
4,7,10,13,16,19-六氧雜二十二烷-21-炔酸
CAS NO:1951438-84-8
MDL NO:MFCD28950778
分子式:C16H28O8
分子量:348.4
純 度:≥95%
結(jié)構(gòu)式:
用 途:僅供科研實(shí)驗(yàn)使用,不用于診治
外 觀(guān):粘稠液體或者固體粉末,取決于分子量
注意事項(xiàng):取用一定要干燥,避免頻繁的溶解和凍干
溶解性:溶于大部分有機(jī)溶劑,如:DCM、DMF、DMSO、THF等等。在水中有很好的溶解性。
產(chǎn)品簡(jiǎn)介:
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
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