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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> ZYG11B蛋白抗體
產(chǎn)品型號
品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時間:2018-06-05 03:06:57瀏覽次數(shù):368次
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英文名稱 ZYG11B
中文名稱 ZYG11B蛋白抗體
別 名 KIAA1730; Protein zyg-11 homolog B; ZY11B_HUMAN; zyg-11 family member B, cell cycle regulator; ZYG11; Zyg11b.
說 明 書 0.2ml
研究領(lǐng)域 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
細(xì)胞定位 細(xì)胞核
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZYG11B
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Function:
Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC.
Subunit:
Interacts with TCEB1/Elongin C. Part of an E3 ubiquitin ligase complex including ZYG11B, CUL2 and Elongin BC.
Similarity:
Belongs to the zyg-11 family.
Contains 2 ARM repeats.
Contains 3 LRR (leucine-rich) repeats.xy-9428R Tal1T細(xì)胞急性淋巴細(xì)胞性白血病1蛋白/淋巴瘤蛋白5抗體
xy-9429R TXNDC9胚胎干細(xì)胞相關(guān)蛋白TXNDC9抗體
xy-9812R TCF9轉(zhuǎn)錄因子9抗體
xy-1663R THOC2轉(zhuǎn)錄因子THOC2抗體
xy-9870R Thymosin beta 4胸腺素β4抗體
xy-4907R TGF beta 3轉(zhuǎn)移生長因子β3(TGFβ3)抗體
xy-4908R TGF beta 1轉(zhuǎn)化生長因子β(TGFβ)抗體
xy-4909R TGF beta 2轉(zhuǎn)化生長因子β2(TGFβ2)抗體
xy-7579R TXNDC5硫氧還蛋白5抗體
xy-9861R CMD1G擴(kuò)張型心肌病蛋白1G抗體
xy-7602R TIAF1TGFB1誘導(dǎo)抗凋亡因子1抗體
xy-6434R Tartrate Resistant Acid Phosphatase端粒酶調(diào)節(jié)相關(guān)蛋白抗體
xy-8197R TAAL6腫瘤相關(guān)蛋白抗原L6抗體
xy-8212R TEF4轉(zhuǎn)錄增強因子TEF4抗體
xy-2185R TDRD9缺氧誘導(dǎo)蛋白HIG1抗體
xy-11683R THOP1Thimet內(nèi)肽酶抗體
xy-9568R TNIP1腫瘤壞死因子誘導(dǎo)蛋白3相互作用蛋白1抗體
xy-6413R Tetranectin四連接素TN抗體
xy-1919R TLR1Toll樣受體1抗體
xy-1920R TOP2 alphaDNA拓普西異構(gòu)酶ⅡA抗體
xy-1921R TFF2三葉肽因子2抗體
xy-1922R TRF2端粒結(jié)合蛋白2抗體
xy-1924R TSARG7精子形成相關(guān)凋亡蛋白7抗體
xy-1908R TEP1端粒酶相關(guān)蛋白1抗體
xy-1911R TGM3谷氨酰胺轉(zhuǎn)胺酶3抗體
xy-9148R RNF92環(huán)指蛋白92抗體
xy-9151R TRIM41環(huán)指蛋白調(diào)節(jié)蛋白激酶C蛋白抗體
xy-9152R TRIM50TRIM50蛋白抗體
xy-9153R RNF88環(huán)指蛋白88抗體
xy-9154R TRIAD3鋅指蛋白抑制NFκB蛋白抗體
xy-9155R RNF98環(huán)指蛋白98抗體
xy-9161R RNF16環(huán)指蛋白16抗體
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