14-3-3τ蛋白抗體

英文名稱 14-3-3 Tau
中文名稱 14-3-3τ蛋白抗體
別    名 14 3 3 protein T cell; 14 3 3 protein tau; 14 3 3 protein theta; 14 3 3 tau; 14 3 3 theta; 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 1433T_HUMAN; 1C5; HS1; KCIP1; Protein HS1; Protein kinase C inhibitor protein 1; Protein tau; tyr3/trp5 monooxygenase activation protein, theta; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide; YWHAQ.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞凋亡  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 14-3-3 Tau
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon. 

Subcellular Location:
Cytoplasm. In neurons, axonally transported to the nerve terminals.

Tissue Specificity:
Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.

Post-translational modifications:
Ser-232 is probably phosphorylated by CK1.xy-2784R    ITKIL-2誘導(dǎo)型T細(xì)胞激酶抗體
xy-15568R    IGF2ASIGF2基因的互補(bǔ)基因1蛋白抗體
xy-15551R    IFI44L干擾素誘導(dǎo)蛋白44樣蛋白抗體
xy-10028R    ITGB4整合素β4抗體
xy-15575R    IGKV A18kappa輕鏈可變區(qū)抗體
xy-2583R    ICOS/CD278誘導(dǎo)協(xié)同刺激分子CD278抗體
xy-2630R    IL-31白細(xì)胞介素31抗體
xy-2627R    IL-28A/IFNL2白細(xì)胞介素28A抗體
xy-2632R    IL-32/NK4白介素32抗體
xy-2633R    IL-33/NFHEV白介素33抗體
xy-2634R    ILT2/CD85j細(xì)胞表面免疫球蛋白樣轉(zhuǎn)錄因子2抗體
xy-2635R    Integrin alpha 2/CD49b整合素α2抗體
xy-2636R    Integrin alpha 2b/CD41血小板膜糖蛋白ⅡbⅢa抗體
xy-2607R    IL-17RC/IL-17RL白介素17受體C抗體
xy-2584R    IGSF8免疫球蛋超家族成員8抗體
xy-2208R    IL-33白介素33抗體
xy-7715R    Importin 9核蛋白9抗體（Ran結(jié)合蛋白M）
xy-3840R    eIF3A真核翻譯起始因子3A抗體
xy-4003R    phospho-eIF4G (ser1185)磷酸化真核翻譯起始因子4G抗體
xy-2055R    Integrin alpha 4+Beta 7整合素α4β7抗體
xy-9278R    phospho-IRF3 (Ser386)磷酸化干擾素調(diào)節(jié)因子3抗體
xy-9025R    ISLR2ISLR2蛋白抗體
xy-9022R    IQCGIQCG蛋白抗體
xy-9023R    IQCKIQCK蛋白抗體
xy-6541R    Id1DNA結(jié)合抑制因子1抗體
xy-6256R    IMPDH1肌苷單磷酸脫氫酶1抗體
xy-6653R    IFI78干擾素誘導(dǎo)蛋白P78抗體
xy-6686R    ICAM5細(xì)胞間粘附分子5抗體
xy-6248R    IMPAD1肌醇單磷酸酶IMPA3抗體
xy-5791R    Integrin Alpha V + Beta 6整合素αVβ6抗體
xy-6759R    IL-11RA白介素11受體α/IL-11Rα抗體
xy-11013R    ILDR1免疫球蛋白樣結(jié)構(gòu)域受體1抗體
xy-10123R    IKK Alpha + IKK betaKB抑制蛋白激酶α/β抗體 IKK α/IKK β
xy-7023R    Interferon alpha 11干擾素α11抗體
xy-7024R    IFNA10干擾素α10抗體
xy-7022R    IFNAR2干擾素α受體2抗體
xy-7021R    IFNA21干擾素α21抗體
xy-6304R    IFNA4干擾素α4抗體
xy-6330R    Interferon alpha 16干擾素α16抗體