5-羥色胺受體1F抗體

英文名稱 5HT1F Receptor
中文名稱 5-羥色胺受體1F抗體
別    名 SR-1F; 5 HT 1F; 5 HT1F; 5 hydroxytryptamine (serotonin) receptor 1F; 5 hydroxytryptamine 1F receptor; 5 hydroxytryptamine receptor 1E beta; 5 hydroxytryptamine receptor 1F; 5 hydroxytryptamine serotonin receptor 1E beta; 5 hydroxytryptamine serotonin receptor 1F; 5HT 1F; 5HT1F; HTR 1F; HTR1EB; HTR1EL; HTR1F; MR 77; MR77; Serotonin receptor 1E beta; Serotonin receptor gene; 5HT1F_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  細(xì)胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, hu,mo,rat,shp,dog,coe,pig,Rb
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT1F Receptor/SR-1F
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Function:
5HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5HT1F is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen. xy-11917R    HRG1神經(jīng)調(diào)節(jié)蛋白1β2抗體
xy-8318R    HDHD3HDHD3蛋白抗體
xy-8320R    HEATR3HEATR3蛋白抗體
xy-8321R    HEATR6乳腺癌增強(qiáng)蛋白抗體
xy-8188R    Histone H3 (mono methyl K79)單甲基組蛋白H3K9抗體
xy-8319R    HDHD2BHDHD2B蛋白抗體
xy-7626R    HAX1造血干細(xì)胞特異性相關(guān)結(jié)合蛋白1抗體
xy-15408R    H-2DdI類組織相容性H-2抗原D-Dalpha鏈抗體
xy-15440R    HEATR5AHEAT重復(fù)內(nèi)含蛋白5A蛋白抗體
xy-0244R    HSP70熱休克蛋白70抗體
xy-11407R    HSD17B8羥類固醇脫氫酶17β抗體（17β-HSD8）
xy-15402R    HABP4透明質(zhì)酸結(jié)合蛋白4抗體
xy-2285R    H5N1 HemagglutininA型流感病毒H5N1凝集素抗體
xy-4619R    H1N1++H3N2 nucleocapsid proteinA型流感病毒核衣殼蛋白抗體
xy-4620R    H1N1+H5N1+H3N2 nucleocapsid proteinA型流感病毒核衣殼蛋白抗體
xy-4621R    H1N1+H5N1+H3N2 nucleocapsid proteinA型流感病毒核衣殼蛋白抗體
xy-15403R    Haemophilus influenza BB型流感病毒蛋白抗體
xy-4623R    HPV16-E7人類乳頭狀瘤病毒16-E7抗體
xy-6281R    Hepsin跨膜蛋白酶絲氨酸1抗體
xy-6297R    HLC3肺癌癌基因蛋白3抗體
xy-4589R    High density lipoprotein高密度脂蛋白抗體
xy-6265R    HEF1蛋白激酶底物相關(guān)蛋白抗體
xy-4942R    HIV1 p55+p24+p17艾滋病病毒抗體
xy-2137R    H3N2 hemagglutinin流感病毒H3N2血凝素抗體
xy-8547R    HPV16 L2人乳頭瘤病毒16型L2抗體
xy-10299R    H7N9 Matrix Protein 1A型禽流感病毒H7N9 M1蛋白抗體
xy-9508R    Hirudin水蛭素抗體
xy-4068R    HuC副腫瘤綜合癥小腦變性相關(guān)蛋白抗體
xy-4518R    Hsp93植物熱休克蛋白93抗體
xy-2212R    rHPV重組人乳頭瘤病毒抗體
xy-5064R    HADHA長鏈烯脂酰輔酶A脫氫酶抗體
xy-5065R    HADHB羥輔酶A脫氫酶β抗體
xy-5067R    HMGCL三羥基*基輔酶A裂解酶抗體