甘草次酸表面修飾靶向脂質(zhì)體

西安瑞禧生物科技有限公司于納米載體（包括納米粒、脂質(zhì)體、膠束等）的*學(xué)應(yīng)用與技術(shù)開發(fā)，并已在、蛋白、常規(guī)化、活體造影劑的納米載體構(gòu)建及方面積累了經(jīng)驗(yàn).

甘草次酸表面修飾靶向脂質(zhì)體

Objective: To study the preparation of liposomes surface modified with glycyrrhetinic acid targeting to hepatocytes. Method: 3 succinic 30 stearyl glycyrrhetinic acid(Suc GAOSt), one of the amphiphilic glycyrrhetinic acid derivatives, was synthesized as targeting molecules, liposomes surface modified with glycyrrhetinic acid has been produced with ethanol injection method. Result: Targeting molecules can be mixed into the liposomal membrane. It was confirmed that the targeting molecules is 9% of the total lipids at the most in the liposomes. Conclusion: Liposomes surface modified with glycyrrhetinic acid was successfully prepared,which is considered to be a potential approach targeting to hepatocytes.

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溫馨提示：西安瑞禧生物科技有限公司供應(yīng)的產(chǎn)品用于科研，不能用于人體、開發(fā)、和其他商業(yè)用途，如有購買方或第三方采購我公司的產(chǎn)品用于、開發(fā)或商業(yè)用途，購買方或第三方將承擔(dān)法律責(zé)任，我公司也將追究其法律責(zé)任以上產(chǎn)品均可定制(2019.10AXC)