氯膦酸二鈉脂質(zhì)體(陰離子)Clodronate Liposomes
氯膦酸二鈉脂質(zhì)體(陰離子)Clodronate Liposomes
西安瑞禧生物科技有限公司是的磷脂,我們除了提供和磷脂,還提供脂質(zhì)體的定制服務(wù),我公司提供的脂質(zhì)體用于大學(xué)實(shí)驗(yàn)室及科研院所里的科學(xué)研究,不能用于人體及開發(fā)或其他型用途。
我公司提供為,個(gè)性化較的脂質(zhì)體試劑,包括空白對(duì)照脂質(zhì)體,脂質(zhì)體,裝載DNA或小分子脂質(zhì)體,長(zhǎng)脂質(zhì)體,陽離子脂質(zhì)體,熒光脂質(zhì)體及其他復(fù)雜的脂質(zhì)體試劑。
我們還可以根據(jù)客戶的需求,使用的磷脂基材或者配方需要來定制復(fù)雜及多樣化的脂質(zhì)體試劑。
以下一些的脂質(zhì)體試劑介紹:
1: 氯膦酸二鈉脂質(zhì)體 一種剔除巨噬的脂質(zhì)體
我們可以提供中性的和陰離子的氯膦酸二鈉脂質(zhì)體,我們也可以提供空白對(duì)照的中性的和陰離子的氯膦酸二鈉脂質(zhì)體產(chǎn)品,該產(chǎn)品我們可以提供懸浮液和凍干粉2種狀態(tài)。
西安瑞禧生物科技有限公司提供兩種預(yù)埋有氯磷酸鹽分子的中性脂質(zhì)體產(chǎn)品,該產(chǎn)品單次靜脈或腹腔注射后可在脾臟經(jīng)巨噬率可達(dá)80-90%,并具有度活性、穩(wěn)定的理化性質(zhì)(冰箱存放后仍保持均一性及懸浮特性),粘滯度低使用,適用于靜脈、腹腔、皮下、鼻腔、氣管等多種方式。
產(chǎn)品介紹:
英文名:Lyophilized-Clodronate Liposomes (Neutral)
中文名:凍干粉氯膦酸二鈉脂質(zhì)體(中性)
Clodronate disodium (liposome encapsulated): 5 mg/mL
Lipid composition: phosphatidylcholine and cholesterol
Shelf-life: 12 months for dry cake (guaranteed, replacement only)
Shelf-life: 3 months sterilely reconstituted (guaranteed, replacement only)
Recommended storage: 2-8 ℃
:電詢
:西安瑞禧生物科技有限公司
英文名:Lyophilized-Clodronate Liposomes (Anionic)
中文名:凍干粉氯膦酸二鈉脂質(zhì)體(陰離子)
Clodronate disodium (liposome encapsulated): 5 mg/mL
Lipid composition: phosphatidylcholine and cholesterol
Shelf-life: 12 months for dry cake (guaranteed, replacement only)
Shelf-life: 3 months sterilely reconstituted (guaranteed, replacement only)
Recommended storage: 2-8 ℃
:電詢
:西安瑞禧生物科技有限公司
我們還可以提供這個(gè)產(chǎn)品的空白對(duì)照脂質(zhì)體及懸浮液脂質(zhì)體產(chǎn)品。
2:脂質(zhì)體(擁有大學(xué)實(shí)驗(yàn)室的科學(xué)研究 不用于人體及開發(fā))
目前我們可以對(duì)一些脂溶性進(jìn)行包裹,比如有紫杉醇、多西紫杉醇、阿霉素、兩性霉素B、姜黃素,伊立替康等等.
磷脂基材上 我們可以選擇HSPC/CHOL/mPEG2000-DSPE等作為基材,我們也可以接受一些復(fù)雜的定制服務(wù)。
Doxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®. The liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL®) allows the researchers to perform experiments at higher concentration/doses.
Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
Lipid concentration: 40.0 mM
Doxorubicin HCl: 4.0 mg/mL
Encapsulation efficiency: > 95% (typically 98%)
Loading battery: 250 mM ammonium sulfate
Mean particle size: 85 nm (80 - 90 nm)
External solution: 10% sucrose, 10 mM histidine, pH 6.5
Shelf-life: 6 months, storage: 2-8 degree C
HSPC: hydrogenated phosphatidylcholine (Soy)
CHOL: cholesterol
mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
3:裝載DNA/RNA/抗體/多肽或小分子脂質(zhì)體試劑(擁有大學(xué)實(shí)驗(yàn)室的科學(xué)研究 不用于人體及開發(fā))
我公司可提供脂質(zhì)基材包裹的DNA/RNA/抗體/多肽或小分子的脂質(zhì)體試劑產(chǎn)品,該類產(chǎn)品用于實(shí)驗(yàn)室的科學(xué)研究,我們可以根據(jù)科研客戶的路線要求以及所需要包裹的具體分子來選用的不同的磷脂基材做成脂質(zhì)體試劑。
4:陽離子脂質(zhì)體
瑞禧生物供應(yīng)一系列的陽離子脂質(zhì)體,用于需帶正電荷的脂質(zhì)體或轉(zhuǎn)染質(zhì)粒DNA、反義/干擾RNA等。
Product Description
DOTAP/DOPE Cationic Liposomes
Specifications
Volume: 2.0mL
Lipid composition: DOTAP/DOPE (50:50 mol/mol)
Mean particle size: 90-110 nm (by DSL)
Lipid concentration: 5 mM (3.61 mg/mL)
Bulk solution: DEPC water, 10% Ethanol, pH 6.0 - 7.0
DOTAP: 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
DOPE: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
5:熒光脂質(zhì)體
西安瑞禧生物供應(yīng)預(yù)制熒光標(biāo)記的脂質(zhì)體,包括常規(guī)熒光脂質(zhì)體、化的熒光脂質(zhì)體以及Avdinized化的熒光脂質(zhì)體,另外還提供客戶定制的熒光脂質(zhì)體(脂類及染料可選)。
我公司可以根據(jù)客戶需要提供復(fù)雜的熒光脂質(zhì)體試劑,熒光物可以選擇。
Product Description
Fluorescent DOPC/CHOL Liposomes Labeled with NBD - PE (100nm)
High quality LUV liposomes labeled with NBD - PE are ready to use. The liposomes are prepared by the extrusion method to 100nm with very tight particle size distribution. The product is sterile filtered and filled in sterile vials guaranteed to be stable for 6 months stored refrigerated . The phospholipid, NBD-PE is labeled on the head group with the environment sensitive fluorophore, NBD (excitation/emission maxima ~463/536 nm)
Specifications
Lipid composition: DOPC/CHOL/NBD-PE (54:45:1 mol/mol)
Lipid concentration: 50 mM (50-55 mM)
NBD - PE: 0.5 mM (0.50 mg/mL)
Mean particle size: 100 nm (90-120 nm)
Hydration buffer: 10% sucrose, 20mM HEPES, pH 7.5 ± 0.2
Storage: in refrigerator (2 - 8 degree C)
Stability: 6 month for unopened vials
DOPC: 1,2-dioleoyl-sn-glycero-3-phosphocholine
CHOL: cholesterol
NBD - PE: N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)-1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt
以上資料源于西安瑞禧生物科技有限公司
如有其他信息或產(chǎn)品信息咨詢請(qǐng)致電我們:
西安瑞禧生物科技有限公司
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