ProZyme成立于1990年, 專業(yè)從事于高品質(zhì)試劑、試劑盒及平臺(tái)的開(kāi)發(fā)，為廣大客戶提供診斷和科研所需的標(biāo)記物、蛋白質(zhì)和酶等。Prozyme于2003年1月收購(gòu)了Glyko®產(chǎn)品線，包括研究糖類的酶及相關(guān)試劑。其中包括Glyko®于1999年收購(gòu)的OxfordGlycoSciences，Ltd.公司的生化試劑產(chǎn)品線。

目前，Prozyme公司可提供商品化的GlykoPrep™ 樣品快速制備平臺(tái)，該平臺(tái)大大加速和簡(jiǎn)化了糖分析樣品的制備流程，其制備的高品質(zhì)產(chǎn)品可用于生化制藥藥物開(kāi)發(fā)和制造。

產(chǎn)品線分布

糖生物研究 其他

GlykoPrep™ 糖樣品快速制備平臺(tái) PhycoLink® 結(jié)合物及活化藻膽蛋白

GlykoPrep™ 糖樣品快速制備平臺(tái) PhycoPro™ 藻膽蛋白

Glyko® 糖生物學(xué)研究工具 鏈親和素及其它蛋白

GlykoPrep™ 糖樣品快速制備平臺(tái)

治療性蛋白質(zhì)的糖基化譜對(duì)其藥理學(xué)性質(zhì)發(fā)揮著重要作用，會(huì)影響免疫原性、藥代動(dòng)力學(xué)和藥效學(xué)。然而，由于目前的手動(dòng)樣品前處理方法復(fù)雜、持續(xù)多日，只能對(duì)開(kāi)發(fā)流程中代表關(guān)鍵決策點(diǎn)的樣品進(jìn)行分析。為了滿足針對(duì)生物仿制藥和新型生物藥物開(kāi)發(fā)日益嚴(yán)格的法規(guī)要求，提供更高的數(shù)據(jù)質(zhì)量和分析通量速度，ProZyme 推出GlykoPrep™ 樣品快速制備平臺(tái)， GlykoPrep-plus*化學(xué)試劑能夠?qū)崿F(xiàn)快速的N-糖鏈消化、標(biāo)記和凈化，為您提供穩(wěn)定和可重現(xiàn)的定量結(jié)果。

該平臺(tái)主要以AssayMAP™小柱（見(jiàn)右圖）為基礎(chǔ)，該小柱包含5μl的填充床，可填充粒徑在20到100μm之間的幾乎所有聚合物、硅膠和凝膠型樹(shù)脂。樣品杯大樣品承載體積為200μl

AssayMAP™小柱可放置在特殊的模塊支架上，結(jié)合相關(guān)的接收板和收集板（96孔式），完成樣品的制備收集。實(shí)驗(yàn)時(shí)，樣品、緩沖液及其它試劑加入到樣品杯中，通過(guò)微孔板離心機(jī)的低速離心處理，溶液流經(jīng)樹(shù)脂填充床。兩塊板同時(shí)使用，可多制備192個(gè)樣品

平臺(tái)特點(diǎn)

● 從純化到聚糖釋放，完成整個(gè)樣本制備流程just 3h, not 3-4 days

● 非選擇性，定量釋放及回收完整的N-聚糖

● 選擇靈活，可實(shí)現(xiàn)高通量（處理1-192個(gè)樣本）

● 室溫標(biāo)記，無(wú)唾液酸損失，標(biāo)記效率>80%

● 與多種自動(dòng)化平臺(tái)的微孔板液體處理系統(tǒng)兼容

Prozyme GKPC-020-P InstantPC CHO mAb N-Linked Glycan Library + CHO mAb Glycoprotein 1 ea (~25 injections) ￥8,560.00

Prozyme GKSQ-020 InstantQ CHO mAb N-Linked Glycan Library ea ￥6,160.00

Prozyme GKSQ-020-P InstantQ CHO mAb N-Linked Glycan Library + CHO mAb Glycoprotein ea ￥8,560.00

Prozyme GS96-HC GlykoPrep® H Cleanup Module (96-ct) ea ￥21,968.00

Prozyme GS24-HC GlykoPrep® H Cleanup Module (24-ct) ea ￥8,784.00

Prozyme GKE-5006B N-Glycanase® 200mU in 80 µl ￥7,136.00

Prozyme GPPNG-APTSX GlykoPrep®-plus Rapid N-Glycan Sample Preparation with APTS (96-ct) (no labware) kit ￥105,680.00

Prozyme GPPNG-LBX GlykoPrep®-plus Rapid N-Glycan Sample Preparation with InstantAB™ (no labware) kit ￥104,864.00

Prozyme CJ95 Horseradish Peroxidase Conjugate Stabilizer ml ￥6.72

Prozyme CJ95 Horseradish Peroxidase Conjugate Stabilizer ≥ 1 L ml ￥5.92

Prozyme CJ90 Alkaline Phosphatase Conjugate Stabilizer ml ￥6.72

Prozyme CJ90 Alkaline Phosphatase Conjugate Stabilizer ≥ 1 L ml ￥5.92

Prozyme FC20 Protein A mg ￥84.48

Prozyme FC20 Protein A ≥ 1,000 mg mg ￥25.28

Prozyme CJ31H Streptavidin-Horseradish Peroxidase Conjugate (IHC)≥ 10 ml ml ￥880.00

Prozyme CJ31H Streptavidin-Horseradish Peroxidase Conjugate (IHC)≥ 3 ml ml ￥1,088.00

Prozyme CJ30H Streptavidin-Horseradish Peroxidase Conjugate (ELISA)≥ 3 ml ml ￥1,088.00

Prozyme CJ30H Streptavidin-Horseradish Peroxidase Conjugate (ELISA)≥ 10 ml ml ￥880.00

Prozyme CJ30R Streptavidin-Agarose≥ 3 ml ml ￥1,088.00

Prozyme SA26 Streptavidin-plus® (recombinant)≥100 mg mg ￥65.60

Prozyme SA20 Streptavidin-plus® ≥ 100 mg mg ￥131.20

Prozyme SA26 Streptavidin-plus® (recombinant)≥10 mg mg ￥576.00

Prozyme SA10 Streptavidin ≥ 1,000 mg mg ￥35.20

Prozyme SA20 Streptavidin-plus® ≥ 10 mg mg ￥992.00

Prozyme SA10 Streptavidin ≥ 100 mg mg ￥65.60

Prozyme PB32 R-Phycoerythrin (red algae)≥ 10 mg mg ￥416.00

Prozyme SA10 Streptavidin≥ 10 mg mg ￥576.00

Prozyme PJ3SX Streptavidin-Phycoerythrin Sampler Kit 1 kit ￥1,696.00

Prozyme PJ31K R-Phycoerythrin Conjugation Kit 1 kit ￥7,184.00

Prozyme PJ25C Activated Allophycocyanin 1 mg ￥1,696.00

Prozyme PJRC10 Activated R-Phycoerythrin 1 mg ￥1,264.00

Prozyme PJ27S Streptavidin-Allophycocyanin 1 mg ￥5,072.00

Prozyme PJ25S Streptavidin-Allophycocyanin 1 mg ￥5,072.00

Prozyme PJ252P1 anti-GST (Type 1)-Allophycocyanin Conjugate ≥ 1 mg mg ￥6,752.00

Prozyme PJ252P1 anti-GST (Type 1)-Allophycocyanin Conjugate 0.25 mg ￥3,376.00

Prozyme PJ255 anti-FLAG® Allophycocyanin Conjugate ≥ 1 mg mg ￥20,272.00

Prozyme PJ255 anti-FLAG® Allophycocyanin Conjugate 0.25 mg ￥5,920.00

Prozyme GKI-4730G Glyko® GlycoSep™ N Plus Guard Column 4.6mm x 1cm ￥10,384.00

Prozyme GKRP-3500 Glyko® Monosaccharide Standard Set 3 vials (100 nmol of ea monosaccharide/vial) ￥5,728.00

Prozyme GKAD-02019 Glyko® LS-Tetrasaccharide c (LST c) 250 µg ￥6,336.00

Prozyme GKAD-01018 Glyko® LS-Tetrasaccharide b (LST b) 0.5 mg ￥12,256.00

Prozyme GKAD-01017 Glyko® LS-Tetrasaccharide a (LST a) 1 mg ￥12,256.00

Prozyme GKAD-02020 Glyko® Disialyllacto-N-tetraose (DSLNT) 200 µg ￥4,352.00

Prozyme GKAD-02013 Glyko® 6'-Sialyllactose (6'-SL) 500 µg ￥4,352.00

Prozyme GKAD-01015 Glyko® 6'-Sialyl-N-acetyllactosamine (6'-SLN) 500 µg ￥4,352.00

Prozyme GKAD-02012 Glyko® 3'-Sialyllactose (3'-SL) 2 mg ￥6,336.00

Prozyme GKAD-01014 Glyko® 3'-Sialyl-N-acetyllactosamine (3'-SLN) 500 µg ￥4,352.00

Prozyme GKAD-00116 Glyko® 3'-Sialyl-3-fucosyllactose (3'-S,3-FL) 100 µg ￥3,168.00

Prozyme GKAD-00135 Glyko® Trifucosyllacto-N-hexaose (TFLNH) 100 µg ￥3,760.00

Prozyme GKAD-00133 Glyko® Monofucosyllacto-N-hexaose III (MFLNH-III) 100 µg ￥3,760.00

Prozyme GKAD-02003 Glyko® Lactodifucotetraose (LDFT) 2 mg ￥4,752.00

Prozyme GKAD-02004 Glyko® Lacto-N-tetraose (LNT) 0.5 mg ￥4,752.00

Prozyme GKAD-02005 Glyko® Lacto-N-neotetraose (LNnT) 500 µg ￥7,520.00

Prozyme GKAD-01024 Glyko® Lacto-N-neohexaose (LNnH) 250 µg ￥5,936.00

Prozyme GKAD-00523 Glyko® Lacto-N-hexaose (LNH) 500 µg ￥6,336.00

Prozyme GKAD-00509 Glyko® Lacto-N-fucopentaose V (LNFP V) 500 µg ￥7,520.00

Prozyme GKAD-00508 Glyko® Lacto-N-fucopentaose III (LNFP III) 500 µg ￥7,520.00

Prozyme GKM-002900 Glyko® Oligomannose 9 (Man9) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKM-002800 Glyko® Oligomannose 8 (Man8) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKM-002700 Glyko® Oligomannose 7 (Man7) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKM-002600 Glyko® Oligomannose 6 (Man6) 10 µg (1 x 10 µg) ￥4,352.00

Prozyme GKC-046300 Glyko® NA4 (G4) 10 µg (1 x 10 µg) ￥4,752.00

Prozyme GKC-035300 Glyko® NA3 (G3) 10 µg (1 x 10 µg) ￥4,752.00

Prozyme GKC-224300 Glyko® A2 (G2S2. α(2,6)) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKC-224301 Glyko® A2F (G2FS2. α(2,6)) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKC-124300 Glyko® A1 (G2S1. α(2,6)) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKC-124301 Glyko® A1F (G2FS1. α(2,6)) 10 µg (1 x 10 µg) ￥4,752.00

Prozyme GKM-002500 Glyko® Oligomannose 5 (Man5) 10 µg (1 x 10 µg) ￥4,352.00

Prozyme GKC-024311 Glyko® NA2FB (G2FB) 10 µg (1 x 10 µg) ￥6,928.00

Prozyme GKC-024301 Glyko® NA2F (G2F) 10 µg (1 x 10 µg) ￥6,928.00

Prozyme GKC-005300 Glyko® NGA3 (A3) 10 µg (1 x 10 µg) ￥4,752.00

Prozyme GKC-024300 Glyko® NA2 (G2) 10 µg (1 x 10 µg) ￥4,352.00

Prozyme GKC-006300 Glyko® NGA4 (A4) 10 µg (1 x 10 µg) ￥5,728.00

Prozyme GKC-014301 Glyko® NA2G1F (G1F) 10 µg (1 x 10 µg) ￥8,496.00

Prozyme GKC-004300 Glyko® NGA2 (G0) 10 µg (1 x 10 µg) ￥4,752.00

Prozyme GKC-004301 Glyko® NGA2F (G0F) 10 µg (1 x 10 µg) ￥8,496.00

Prozyme GKSP-313 Glyko® APTS A2F (G2FS2. α(2,6)) 60 pmol ￥2,768.00

Prozyme GKSP-520 Glyko® APTS Biantennary & High Mannose Partitioned Library 120 pmol ￥18,288.00

Prozyme GKSP-316 Glyko® APTS NA2G1F (G1F) 60 pmol ￥2,768.00

Prozyme GKSP-301 Glyko® APTS NGA2 (G0) 60 pmol ￥2,768.00

Prozyme GKSP-302 Glyko® APTS NGA2F (G0F) 60 pmol ￥2,768.00

Prozyme GKSP-304 Glyko® APTS NA2 (G2) 60 pmol ￥2,768.00

Prozyme GKSP-305 Glyko® APTS NA2F (G2F) 60 pmol ￥2,768.00

Prozyme GKSP-317 Glyko® APTS NA2G1 (G1) 60 pmol ￥2,768.00

Prozyme GKSP-500 Glyko® APTS Bracketing Standard (DP2 & DP15) 120 pmol ￥7,120.00

Prozyme GKSA-005 Glyko® 2-AA Human IgG N-Linked Glycan Library 200 pmol ￥6,160.00

Prozyme GKSA-001 Glyko® 2-AA Human α1-Acid Glycoprotein N-Linked Glycan Library 200 pmol ￥5,808.00

Prozyme GKSA-002 Glyko® 2-AA Bovine Fetuin N-linked Glycan Library 200 pmol ￥5,264.00

Prozyme GKSA-107 Glyko® 2-AA Oligomannose 9 (Man9) 100 pmol ￥2,544.00

Prozyme GKSA-106 Glyko® 2-AA Oligomannose 8 (Man8) 100 pmol ￥2,544.00

Prozyme GKSA-105 Glyko® 2-AA Oligomannose 7 (Man7) 100 pmol ￥2,544.00

Prozyme GKSA-104 Glyko® 2-AA Oligomannose 6 (Man6) 100 pmol ￥2,544.00

Prozyme GKSA-103 Glyko® 2-AA Oligomannose 5 (Man5) 100 pmol ￥2,544.00

Prozyme GKSA-311 Glyko® 2-AA A1 (G2S1. α(2,6)) 100 pmol ￥2,544.00

Prozyme GKSA-315 Glyko® 2-AA A1F (G2FS1. α(2,6)) 100 pmol ￥2,544.00